Expressions of IGF-1, pAKT, and pS6 in Uterosacral Ligaments of Patients with Pelvic Organ Prolapse
The expressions of IGF-1, pAKT, pS6, and type I and type III collagen decreased in the uterosacral ligament tissues of POP patients, and the IGF-1/AKT/mTORC1 signaling pathway regulated by IGF-1 may be related to the occurrence of POP.
Authors
- Hongling Xu
- Dongdi Xu
- Xuemei Wang (ORCID: https://orcid.org/0000-0002-3516-0966)
- Qing Li (ORCID: https://orcid.org/0000-0003-4540-7915)
- Gen‐Sheng Wang
Institutions
- Anqing City Hospital (CN)
Publication Details
- Journal
- International Urogynecology Journal
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1007/s00192-025-06174-2
- Citations
- 2
- Primary Topic
- Pelvic floor disorders treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.34