Insights into the E2F target genes in breast cancer: associations of pathway genes with prognosis and immune cell filtration based on in silico and ex vivo analyses
These findings suggest that E2F target genes, including JPT1 and TBRG4, may act as prognostic biomarkers and contribute to immune evasion in BC. E2F target genes can also offer good potential for classifying and treating patients.
Authors
- Mohammad Mahdevar (ORCID: https://orcid.org/0000-0002-9042-3466)
- Atefeh Zamani
- Nadia Manavi Manavi
- Behnoosh Nikonezhad
- Maryam Lotfian
Institutions
- Hamedan University of Medical Sciences (IR)
- Islamic Azad University, Mashhad (IR)
- University of Tehran (IR)
- Iran University of Science and Technology (IR)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1186/s12935-025-03839-2
- Citations
- 4
- Primary Topic
- Cancer-related Molecular Pathways
- Type
- article
- Field-Weighted Citation Impact
- 4.18