Early radiotherapy improved survival of patients with extensive-stage small cell lung cancer treated with first-line chemo-immunotherapy
Administering early radiotherapy significantly improved both PFS and OS in patients with ES-SCLC treated with first-line chemo-immunotherapy with tolerable adverse events, while salvage radiotherapy did not improve survival. This finding warrants further validation through prospective randomized studies.
Authors
- Jingyi Jia (ORCID: https://orcid.org/0000-0002-0552-081X)
- Yifei Lü (ORCID: https://orcid.org/0000-0001-8907-4898)
- Zhangru Yang (ORCID: https://orcid.org/0000-0001-5579-0159)
- Xiaolong Fu (ORCID: https://orcid.org/0000-0001-8127-3884)
- Xuwei Cai
- Lei Zhao (ORCID: https://orcid.org/0000-0002-1233-9189)
- Yunfeng Wang (ORCID: https://orcid.org/0000-0001-6658-6276)
- Xi Su
- Ya Zeng
- Tongfang Zhou
Institutions
- Shanghai Chest Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1186/s12885-025-14417-0
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China