An Uncommon Maxillary Presentation of Aggressive Central Giant Cell Granuloma in a Child: Clinical and Radiological Insights

Background Central Giant Cell Granuloma (CGCG) is a benign intraosseous lesion of the jaws, exhibiting a variable clinical course. The aggressive variant is characterized by rapid expansion, cortical perforation, and a higher recurrence rate. Maxillary involvement, particularly in pediatric patients, is rare and often poses diagnostic and therapeutic challenges.  Case Presentation This case report describes a 13-year-old female presenting with a rapidly enlarging, painless swelling in the anterior maxilla. Clinical, radiographic, and histopathological findings confirmed the diagnosis of aggressive CGCG. Cone-beam computed tomography revealed cortical breach with extension into the maxillary sinus and nasal cavity. Surgical excision under general anesthesia was performed, followed by splint placement. Postoperative recovery was uneventful, and the patient remains under regular follow-up with no signs of recurrence to date.  Conclusion Early diagnosis and surgical intervention are crucial in managing aggressive CGCG, especially in pediatric patients, to prevent functional and esthetic complications. Radiographic assessment and histopathological confirmation remain vital for appropriate treatment planning and minimizing recurrence risk.

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Publication Details

Published
2025-06-06
DOI
https://doi.org/10.38124/ijisrt/25may1892
Primary Topic
Bone Tumor Diagnosis and Treatments
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article
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article

An Uncommon Maxillary Presentation of Aggressive Central Giant Cell Granuloma in a Child: Clinical and Radiological Insights

Ashwini Baliga, Ujwala Shetty, D Raghavendra, Kavya Kavya et al.
Bone Tumor Diagnosis and Treatments
article

An Uncommon Maxillary Presentation of Aggressive Central Giant Cell Granuloma in a Child: Clinical and Radiological Insights

Ashwini Baliga, Ujwala Shetty, D Raghavendra, Kavya Kavya, Roopashri Rajesh Kashyap, Gowri P Bhandarkar
article en

Abstract

Background Central Giant Cell Granuloma (CGCG) is a benign intraosseous lesion of the jaws, exhibiting a variable clinical course. The aggressive variant is characterized by rapid expansion, cortical perforation, and a higher recurrence rate. Maxillary involvement, particularly in pediatric patients, is rare and often poses diagnostic and therapeutic challenges.  Case Presentation This case report describes a 13-year-old female presenting with a rapidly enlarging, painless swelling in the anterior maxilla. Clinical, radiographic, and histopathological findings confirmed the diagnosis of aggressive CGCG. Cone-beam computed tomography revealed cortical breach with extension into the maxillary sinus and nasal cavity. Surgical excision under general anesthesia was performed, followed by splint placement. Postoperative recovery was uneventful, and the patient remains under regular follow-up with no signs of recurrence to date.  Conclusion Early diagnosis and surgical intervention are crucial in managing aggressive CGCG, especially in pediatric patients, to prevent functional and esthetic complications. Radiographic assessment and histopathological confirmation remain vital for appropriate treatment planning and minimizing recurrence risk.

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Bone Tumor Diagnosis and Treatments
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An Uncommon Maxillary Presentation of Aggressive Central Giant Cell Granuloma in a Child: Clinical and Radiological Insights — Ashwini Baliga, Ujwala Shetty, et al. · (2025) | TGRS Research Map | TGRS