Investigation of the Potential of Commercial and Wild <i>Passiflora</i> Seed Species as Stilbenes Sources

Passion fruit seeds, a byproduct of juice processing, are rich in bioactive stilbenes with health-promoting properties. This study investigated piceatannol and resveratrol in seeds from four commercial and sixteen wild <i>Passiflora</i> species using the μ-QuEChERS method combined with UHPLC-MS/MS analysis. The method showed good analytical performance, with linearity (<i>R</i>² ≥ 0.991), LOQ ≤ 20 μg kg^-1, and RSD < 11%. Piceatannol and resveratrol were found in 70 and 60% of the analyzed species, respectively. Piceatannol was found in significantly higher amounts (0.6-55.2 mg kg^-1) in 95% of these species, with values up to 56 times greater than resveratrol (0.3-7.5 mg kg^-1). The highest piceatannol amounts were observed in the wild species <i>P. longifilamentosa</i> (55.2 mg kg^-1) and <i>P. edulis x P. caerulea</i> (44.7 mg kg^-1). These findings highlight <i>Passiflora</i> seeds as a valuable natural source of piceatannol, supporting their potential applications in functional foods, cosmetics, and pharmaceutical products.