Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study
In this pilot study Elenagen demonstrated efficacy in treatment of OA pain in dogs without side effects. The study has some limitations: small animal number, lack of long-term follow-up, and the outcome is limited to only one parameter, CBPI. Also in future studies the mechanism of anti-OA effect of p62 plasmid should be addressed.
Authors
- Sergey Gvozdev
- М. П. Патапович
- S. Polyakov
- Alexander Shneider
- Evgeny A. Bakin
- Vladimir L. Gabai (ORCID: https://orcid.org/0000-0003-4505-4718)
- S. А. Krasny (ORCID: https://orcid.org/0000-0003-3244-5664)
- M.M. Kardash
- Aliaksei Bazyleuski
- Andrei Yeliseyeu
- Egor Lelikov
- Maxim Harold Langs
- Andrei Borodko
- Robert Devlin
- Yauheni Baranou
Institutions
- ORT Israel (IL)
- San Diego Miramar College (US)
- Belarusian State University (BY)
- Vitebsk State Medical University (BY)
- 9th City Clinical Hospital (BY)
- Boston Engineering (United States) (US)
- Gomel Engineering Institute (BY)
- N.N. Alexandrov National Cancer Centre (BY)
- Grodno State Medical University (BY)
- Institute Belniis (BY)
- Belarusian National Technical University (BY)
- Ariel University (IL)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-06-06
- DOI
- https://doi.org/10.3389/fvets.2025.1519881
- Citations
- 2
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.34