Regional and Global Changes in Brain Structure 1‐Year Post Pediatric “Mild” Traumatic Brain Injury
Current findings suggest a dose-dependent relationship between injury severity and alterations in both global and regional brain structure within the spectrum of pmTBI. Our results emphasize the importance of using objective biomarkers rather than subjective self-reported symptoms to better understand the long-term effects of injury. ANN NEUROL 2025;98:341-353.
Authors
- Andrei A. Vakhtin
- Vadim Zotev (ORCID: https://orcid.org/0000-0002-5784-2562)
- Robert E. Sapién (ORCID: https://orcid.org/0000-0002-8196-9635)
- Andrew R. Mayer (ORCID: https://orcid.org/0000-0003-2396-5609)
- Jingshu Wu
- Timothy B. Meier (ORCID: https://orcid.org/0000-0002-4495-2754)
- Josef M. Ling
- Harm J. van der Horn (ORCID: https://orcid.org/0000-0001-9923-0866)
- J. P. Phillips (ORCID: https://orcid.org/0000-0001-6530-699X)
- Upasana Nathaniel (ORCID: https://orcid.org/0000-0003-4467-8369)
- Tracey V. Wick
- Samuel D. Miller (ORCID: https://orcid.org/0000-0002-6169-3985)
- Richard A. Campbell (ORCID: https://orcid.org/0000-0002-4305-4821)
- Divyasree Sasi Kumar
- Jessica R. McQuaid
- Rahsan Keskin
Institutions
- University Medical Center Groningen (NL)
- Mind Research Network (US)
- University of Groningen (NL)
- University of New Mexico (US)
- Medical College of Wisconsin (US)
- Biomedical Research Institute (US)
Publication Details
- Journal
- Annals of Neurology
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1002/ana.27259
- Citations
- 1
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- National Institutes of Health