Inflammation, Antiretroviral Therapy Continuation, and HIV Disease Progression in Postpartum Women With HIV
Postpartum WHIV with higher levels of immune biomarkers have increased hazards of HIV disease progression, suggesting an important role for inflammation in HIV treatment outcomes. Our results showed that continuation of ART compared to discontinuation had differential impacts on various immune markers, with the discontinuation results relevant in settings of poor adherence, or treatment interruption.
Authors
- Patricia M. Flynn (ORCID: https://orcid.org/0000-0003-4918-6881)
- Allen Matubu (ORCID: https://orcid.org/0000-0001-5361-7686)
- Amita Jain Gupta (ORCID: https://orcid.org/0000-0001-7036-2718)
- Dhayendre Moodley (ORCID: https://orcid.org/0000-0003-1849-9631)
- Rachel Ketchum
- Avy Violari (ORCID: https://orcid.org/0000-0002-9437-776X)
- Daniela Moïsi (ORCID: https://orcid.org/0000-0003-2326-7683)
- Lameck Chinula (ORCID: https://orcid.org/0000-0003-3690-4207)
- Taha E. Taha (ORCID: https://orcid.org/0000-0001-9814-4894)
- Sean S. Brummel (ORCID: https://orcid.org/0000-0002-4116-404X)
- Rupak Shivakoti (ORCID: https://orcid.org/0000-0002-2773-9310)
- Maxensia Owor
- Michael M. Lederman (ORCID: https://orcid.org/0000-0001-9247-8025)
- Mark J Giganti (ORCID: https://orcid.org/0000-0003-2255-9756)
- Judith S. Currier (ORCID: https://orcid.org/0000-0003-4279-4737)
- Sufia Dadabhai (ORCID: https://orcid.org/0000-0002-4965-1440)
- Mary Glenn Fowler (ORCID: https://orcid.org/0000-0003-4484-9009)
Institutions
- University of North Carolina at Chapel Hill (US)
- St. Jude Children's Research Hospital (US)
- Johns Hopkins University (US)
- University of Zimbabwe (ZW)
- University of Malawi (MW)
- University of California, Los Angeles (US)
- University of the Witwatersrand (ZA)
- University Hospitals of Cleveland (US)
- Johns Hopkins Medicine (US)
- Centre for the AIDS Programme of Research in South Africa (ZA)
- Kamuzu Central Hospital (MW)
- Cancer Research And Biostatistics (US)
- MUJHU Research Collaboration (UG)
- Perinatal HIV Research Unit (ZA)
- Columbia University (US)
- University of KwaZulu-Natal (ZA)
Publication Details
- Journal
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1097/qai.0000000000003703
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00