Effects of Plasmodium berghei infection on the expression of salivary gland immune-related genes in the Anopheles stephensi mosquito
The highest expression levels of LRIM8A at both early and late phases of salivary gland infection underscore its potential as a key immune effector. However, further functional assays are required to validate the role of LRIM8A in mosquito innate immunity. A deeper understanding of the immune mechanisms in Anopheles following Plasmodium infection could contribute to the development of novel malaria control strategies.
Authors
- Akram Abouie Mehrizi (ORCID: https://orcid.org/0000-0001-9502-0407)
- Leila Darzi
- Hemn Yousefi
- Sakineh Pirahmadi (ORCID: https://orcid.org/0000-0002-8839-1573)
- Jafar J. Sani
- Abbasali Raz (ORCID: https://orcid.org/0000-0002-7937-8350)
- Flora Forouzesh (ORCID: https://orcid.org/0000-0002-2747-3479)
- Zeinab Mohammadi Firouz
- Zahra Sadat Mousavi Shafi
- Sepideh Siasi
Institutions
- Pasteur Institute of Iran (IR)
- Tarbiat Modares University (IR)
- Islamic Azad University Medical Branch of Tehran (IR)
- Biotechnology Research Center (IR)
Publication Details
- Journal
- Malaria Journal
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1186/s12936-025-05430-6
- Citations
- 2
- Primary Topic
- Invertebrate Immune Response Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- National Science Foundation
- Iran National Science Foundation
- Pasteur Institute of Iran