Polygenic Risk Scores for Type 2 Diabetes in the Swiss HIV Cohort Study

We found that CD4-cell counts are not associated with the risk of T2D, and that neither CD4-cell count nor cumulative exposure to NNRTI or INSTI-class antiretrovirals modify this risk.

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Publication Details

Journal
JAIDS Journal of Acquired Immune Deficiency Syndromes
Published
2025-06-06
DOI
https://doi.org/10.1097/qai.0000000000003702
Primary Topic
HIV-related health complications and treatments
Type
article
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article

Polygenic Risk Scores for Type 2 Diabetes in the Swiss HIV Cohort Study

PHILIP E. TARR, Enos Bernasconi, Matthias L. Cavassini, Flavia Hodel et al.
JAIDS Journal of Acquired Immune Deficiency Syndromes
HIV-related health complications and treatments
article

Polygenic Risk Scores for Type 2 Diabetes in the Swiss HIV Cohort Study

PHILIP E. TARR, Enos Bernasconi, Matthias L. Cavassini, Flavia Hodel, Johannes Nemeth, Bernard Surial, Lauro Damonti, Marcel Stoeckle, Chloé Pasin, Alexandra Calmy, Huldrych F. Günthard, Roger D. Kouyos, Christian Wandall Thorball, Marco Labarile, Julia Notter, Burcu Tepekule, Jacques Fellay
article en

Abstract

We found that CD4-cell counts are not associated with the risk of T2D, and that neither CD4-cell count nor cumulative exposure to NNRTI or INSTI-class antiretrovirals modify this risk.

JAIDS Journal of Acquired Immune Deficiency SyndromesVol. 100(1)
University of Geneva (CH), University of Bern (CH), SIB Swiss Institute of Bioinformatics (CH), University of Basel (CH), Princeton University (US), University of Zurich (CH), University of St.Gallen (CH), University Hospital of Bern (CH), University Hospital of Basel (CH), Kantonsspital Baselland (CH), Ente Ospedaliero Cantonale (CH), University Hospital of Zurich (CH), University Hospital of Geneva (CH), École Polytechnique Fédérale de Lausanne (CH), Università della Svizzera italiana (CH), University of Lausanne (CH)
Good health and well-being
Openalex Percentile: Top 79%
HIV-related health complications and treatments
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