Adherence to guidelines for antibiotics used in the initial treatment of febrile neutropenia in patients with cancer: a study using health insurance claims database in Japan

The study revealed an FN guideline adherence rate of 78.8% in Japan, along with changes in antibiotic prescribing patterns, including a trend toward carbapenem-sparing strategies between 2014 and 2022. Continuous surveillance is necessary, as adherence rates and antibiotic selection may be influenced by future guideline revisions and antimicrobial stewardship initiatives.