Leveraging machine learning and molecular docking techniques to predict novel melanocortin-4 receptor agonists
Monogenic obesity caused by mutations in the melanocortin-4 receptor (MC4R) gene remains a significant health challenge, despite numerous efforts to discover effective treatments. The MC4R has emerged as a promising target for drug development due to its role in energy homeostasis and adipose tissue formation.
Authors
- Vasilis Panagiotopoulos (ORCID: https://orcid.org/0000-0003-1563-2302)
- Eftichia Kritsi (ORCID: https://orcid.org/0000-0002-3975-0832)
- Minos–Timotheos Matsoukas (ORCID: https://orcid.org/0000-0002-4642-8163)
- Paris Christodoulou (ORCID: https://orcid.org/0009-0001-3426-2194)
- Dionisis Cavouras
- Stavroula Giakoumopoulou
Institutions
- University of West Attica (GR)
Publication Details
- Journal
- Folia Medica
- Published
- 2025-06-06
- DOI
- https://doi.org/10.3897/folmed.67.e150583
- Citations
- 1
- Primary Topic
- Regulation of Appetite and Obesity
- Type
- article
- Field-Weighted Citation Impact
- 0.91