Acidic tumor microenvironment–modulated nanoparticle potentiates gastric cancer photoimmunotherapy

Our results revealed that the combination of FX-11@PEG-Ce6-based photodynamic therapy and immunotherapy could achieve a synergistic antitumor effect with excellent biosafety, presenting great therapeutic potential for enhanced photoimmunotherapy for GC.

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Publication Details

Journal
Journal of Advanced Research
Published
2025-06-06
DOI
https://doi.org/10.1016/j.jare.2025.06.008
Primary Topic
Nanoplatforms for cancer theranostics
Type
article
Field-Weighted Citation Impact
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article

Acidic tumor microenvironment–modulated nanoparticle potentiates gastric cancer photoimmunotherapy

Zhixiong Wang, Xueliang Zuo, Longfei Wu, Yi‐Ren He et al.
Journal of Advanced Research
Nanoplatforms for cancer theranostics
article

Acidic tumor microenvironment–modulated nanoparticle potentiates gastric cancer photoimmunotherapy

Zhixiong Wang, Xueliang Zuo, Longfei Wu, Yi‐Ren He, Yao Fei, Bo Zhang, Peng Gao, Juan Cai, Cai Liu, Menglin Zhu
article en

Abstract

Our results revealed that the combination of FX-11@PEG-Ce6-based photodynamic therapy and immunotherapy could achieve a synergistic antitumor effect with excellent biosafety, presenting great therapeutic potential for enhanced photoimmunotherapy for GC.

Journal of Advanced ResearchVol. 81
Wannan Medical College (CN), University of Science and Technology of China (CN), First Affiliated Hospital of Wannan Medical College (CN)
Zero hunger
Openalex Percentile: Top 88%
Nanoplatforms for cancer theranostics
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