Deficits in Long-Term Vaccine Immunity Among Childhood Cancer Survivors Despite Revaccination Programs

Our findings highlight that vaccines are underutilized in CCSs with a notable gap in immunity, particularly among those who have undergone intensive treatments. Unexpectedly, MMR revaccination did not significantly affect rubella immunity. Given the increasing number of CCSs, it is essential to better understand how to effectively restore vaccine immunity in this population.

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Publication Details

Journal
Vaccines
Published
2025-06-06
DOI
https://doi.org/10.3390/vaccines13060617
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
0.00

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article

Deficits in Long-Term Vaccine Immunity Among Childhood Cancer Survivors Despite Revaccination Programs

Teodora Aktas, Maja Jahnmatz, Teghesti Tecleab, Tiia Lepp et al.
Vaccines
Hematopoietic Stem Cell Transplantation
article

Deficits in Long-Term Vaccine Immunity Among Childhood Cancer Survivors Despite Revaccination Programs

Teodora Aktas, Maja Jahnmatz, Teghesti Tecleab, Tiia Lepp, Samuel Hellmän, Eva Tiselius, Anna Nilsson, Alexander Zadruzny
article en

Abstract

Our findings highlight that vaccines are underutilized in CCSs with a notable gap in immunity, particularly among those who have undergone intensive treatments. Unexpectedly, MMR revaccination did not significantly affect rubella immunity. Given the increasing number of CCSs, it is essential to better understand how to effectively restore vaccine immunity in this population.

VaccinesVol. 13(6)
Public Health Agency of Sweden (SE), Karolinska University Hospital (SE), Karolinska Institutet (SE)
Vetenskapsrådet, Barncancerfonden
Good health and well-being
Openalex Percentile: Top 84%
Hematopoietic Stem Cell Transplantation
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