Modeling the Ocular Pharmacokinetics and Pharmacodynamics of Ranibizumab for Improved Understanding and Data Collection Strategies in Ocular Diseases
This study extends our understanding of the ocular pharmacokinetics and pharmacodynamics of ranibizumab and provides theoretical insights for enhanced data collection schemes to be considered for clinical trials and in the development of novel anti-VEGF therapies.
Authors
- Antonello Caruso (ORCID: https://orcid.org/0000-0001-5832-3636)
- Philip K. Maini (ORCID: https://orcid.org/0000-0002-0146-9164)
- Eamonn A. Gaffney (ORCID: https://orcid.org/0000-0002-6888-4362)
- Michael Gertz (ORCID: https://orcid.org/0000-0003-4530-6110)
- Jessica R. Crawshaw (ORCID: https://orcid.org/0000-0003-0797-1144)
Institutions
- Roche (Switzerland) (CH)
- University of Oxford (GB)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1167/iovs.66.6.20
- Citations
- 2
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.41