Cornea Nerves Can Identify Different Types of Parkinson's Disease
As a non-invasive examination method, IVCM holds significant value for differentiating Parkinson's disease subtypes and identifying patients with varying motor manifestations. Among these findings, individuals with PIGD displayed more pronounced corneal nerve damage; furthermore, patients exhibiting lower inferior whorl length, corneal nerve fiber width, and fractal dimension of corneal nerves values were found to be at greater risk of being classified within the PIGD subtype.
Authors
- Lifen Yao
- Xin Jin (ORCID: https://orcid.org/0000-0001-6461-6005)
- Xinyu Zhang (ORCID: https://orcid.org/0000-0002-4426-939X)
- Hong Zhang (ORCID: https://orcid.org/0000-0002-8215-8105)
- Hongwen Yuan (ORCID: https://orcid.org/0000-0002-2556-2718)
- Dongyu Li (ORCID: https://orcid.org/0000-0001-7581-0276)
- Shumin Li (ORCID: https://orcid.org/0000-0002-6037-6523)
- Fan Yang (ORCID: https://orcid.org/0000-0002-8111-4880)
Institutions
- Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1167/iovs.66.6.21
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39