GPR56 function as a key repressor in hepatocyte pyroptosis and the pathogenesis of liver fibrosis
Our study identify GPR56 as a suppressor of hepatocyte pyroptosis and liver fibrosis, underscoring its potential as a therapeutic and diagnostic target.
Authors
- Lina Zheng (ORCID: https://orcid.org/0000-0002-8412-3344)
- Zhemin Shi
- Tao Han (ORCID: https://orcid.org/0000-0003-4216-6968)
- Kun Zhang (ORCID: https://orcid.org/0000-0002-8916-556X)
- Qi Liu (ORCID: https://orcid.org/0000-0002-5684-7396)
- Hong Wei (ORCID: https://orcid.org/0000-0003-1199-4365)
- Mengxia Zhang (ORCID: https://orcid.org/0000-0002-7908-5072)
- Xiaoxiao Du (ORCID: https://orcid.org/0000-0002-2989-5341)
- Yifan He
Institutions
- Tianjin Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1186/s12967-025-06619-8
- Citations
- 2
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Tianjin City