Trends in serum levels of emerging and legacy per- and polyfluoroalkyl substances from 2008 to 2018: a longitudinal study in China

Our study provides information on serum PFAS levels in Chinese retired workers in the Dongfeng-Tongji cohort, and highlights that the risk of exposure to novel PFCAs and PFAS alternatives deserves continued attention. For longitudinal studies with long-term follow-up (e.g. more than 5 years), relying only on a single baseline serum PFAS level may generate misclassification bias resulting in expected bias towards the null and affect the estimation of health effects. https://doi.org/10.1289/EHP15340.

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Publication Details

Journal
Environmental Health Perspectives
Published
2025-06-06
DOI
https://doi.org/10.1289/ehp15340
Citations
6
Primary Topic
Per- and polyfluoroalkyl substances research
Type
article
Field-Weighted Citation Impact
5.16

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article

Trends in serum levels of emerging and legacy per- and polyfluoroalkyl substances from 2008 to 2018: a longitudinal study in China

Meian He, Lu Liu, Jin Zhang, Hong Guo et al.
6 citations
Environmental Health Perspectives
Per- and polyfluoroalkyl substances research
5.16
article

Trends in serum levels of emerging and legacy per- and polyfluoroalkyl substances from 2008 to 2018: a longitudinal study in China

Meian He, Lu Liu, Jin Zhang, Hong Guo, Xu Cheng, Lin Liu, Yu Wang, Junya Gao
article en
6 citations

Abstract

Our study provides information on serum PFAS levels in Chinese retired workers in the Dongfeng-Tongji cohort, and highlights that the risk of exposure to novel PFCAs and PFAS alternatives deserves continued attention. For longitudinal studies with long-term follow-up (e.g. more than 5 years), relying only on a single baseline serum PFAS level may generate misclassification bias resulting in expected bias towards the null and affect the estimation of health effects. https://doi.org/10.1289/EHP15340.

Environmental Health Perspectives
Huazhong University of Science and Technology (CN)
National Natural Science Foundation of China, National Key Research and Development Program of China
Zero hunger
Openalex Percentile: Top 5%
Per- and polyfluoroalkyl substances research
5.16
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Trends in serum levels of emerging and legacy per- and polyfluoroalkyl substances from 2008 to 2018: a longitudinal study in China — Meian He, Lu Liu, et al. · Environmental Health Perspectives (2025) | TGRS Research Map | TGRS