Nano-Silica Particle Exposure Affects Pollen-Sensitized Mice via Nicotinamide Metabolism
Pollen-sensitized mice exposed to nano-SiO<sub>2</sub> particles can aggravate allergic reactions and induce dysregulation of the metabolism characterized by niacin and nicotinamide. Nicotinamide could stabilize mast cells and may serve as a potential therapeutic strategy for allergic diseases. Further, in-depth investigations are needed.
Authors
- Mengda Cao (ORCID: https://orcid.org/0000-0002-7402-5046)
- Yongshi Yang (ORCID: https://orcid.org/0000-0002-3889-4076)
- Yibo Hou (ORCID: https://orcid.org/0000-0001-5582-5243)
- Ji‐Fu Wei (ORCID: https://orcid.org/0000-0001-6412-3251)
- Diandou Xu (ORCID: https://orcid.org/0000-0002-0232-9091)
- Yali Cheng (ORCID: https://orcid.org/0000-0002-5202-3533)
- Jin-Lu Sun
Institutions
- Chinese Academy of Sciences (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Zhongda Hospital Southeast University (CN)
- Jiangsu Cancer Hospital (CN)
- Key Laboratory of Nuclear Radiation and Nuclear Energy Technology (CN)
- Institute of High Energy Physics (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1159/000546393
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 0.00