TimEHR: Image-Based Time Series Generation for Electronic Health Records
Time series in Electronic Health Records (EHRs) present unique challenges for generative models, such as irregular sampling, missing values, and high dimensionality. In this paper, we propose a novel generative adversarial network (GAN) model, TimEHR, to generate time series data from EHRs. In particular, TimEHR treats time series as images by using 2D convolutional kernels and is based on two conditional GANs. The first GAN generates missingness patterns, and the second GAN generates time series values based on the missingness pattern. Experimental results on three real-world EHR datasets show that TimEHR outperforms state-of-the-art methods in terms of fidelity, utility, and privacy metrics.
Authors
- Hojat Karami (ORCID: https://orcid.org/0000-0002-2017-7204)
- Mary‐Anne Hartley (ORCID: https://orcid.org/0000-0002-8826-3870)
- David Atienza (ORCID: https://orcid.org/0000-0001-9536-4947)
- Anisoara Ionescu (ORCID: https://orcid.org/0000-0002-2341-4383)
Institutions
- Intelligent Light (United States) (US)
- Response Technologies (United States) (US)
- École Polytechnique Fédérale de Lausanne (CH)
Publication Details
- Journal
- IEEE Journal of Biomedical and Health Informatics
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1109/jbhi.2025.3577328
- Citations
- 3
- Primary Topic
- Machine Learning in Healthcare
- Type
- article
- Field-Weighted Citation Impact
- 7.44
Funders
- European Commission