TimEHR: Image-Based Time Series Generation for Electronic Health Records

Time series in Electronic Health Records (EHRs) present unique challenges for generative models, such as irregular sampling, missing values, and high dimensionality. In this paper, we propose a novel generative adversarial network (GAN) model, TimEHR, to generate time series data from EHRs. In particular, TimEHR treats time series as images by using 2D convolutional kernels and is based on two conditional GANs. The first GAN generates missingness patterns, and the second GAN generates time series values based on the missingness pattern. Experimental results on three real-world EHR datasets show that TimEHR outperforms state-of-the-art methods in terms of fidelity, utility, and privacy metrics.

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Publication Details

Journal
IEEE Journal of Biomedical and Health Informatics
Published
2025-06-06
DOI
https://doi.org/10.1109/jbhi.2025.3577328
Citations
3
Primary Topic
Machine Learning in Healthcare
Type
article
Field-Weighted Citation Impact
7.44

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article

TimEHR: Image-Based Time Series Generation for Electronic Health Records

Hojat Karami, Mary‐Anne Hartley, David Atienza, Anisoara Ionescu
3 citations
IEEE Journal of Biomedical and Health Informatics
Machine Learning in Healthcare
7.44
article

TimEHR: Image-Based Time Series Generation for Electronic Health Records

Hojat Karami, Mary‐Anne Hartley, David Atienza, Anisoara Ionescu
article en
3 citations

Abstract

Time series in Electronic Health Records (EHRs) present unique challenges for generative models, such as irregular sampling, missing values, and high dimensionality. In this paper, we propose a novel generative adversarial network (GAN) model, TimEHR, to generate time series data from EHRs. In particular, TimEHR treats time series as images by using 2D convolutional kernels and is based on two conditional GANs. The first GAN generates missingness patterns, and the second GAN generates time series values based on the missingness pattern. Experimental results on three real-world EHR datasets show that TimEHR outperforms state-of-the-art methods in terms of fidelity, utility, and privacy metrics.

IEEE Journal of Biomedical and Health InformaticsVol. 29(12)
Intelligent Light (United States) (US), Response Technologies (United States) (US), École Polytechnique Fédérale de Lausanne (CH)
European Commission
Openalex Percentile: Top 3%
Machine Learning in Healthcare
7.44
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