Association of CSF β-Amyloid Biomarker and Imaging Markers in Cerebral Amyloid Angiopathy
Cerebral amyloid angiopathy (CAA) is a small vessel disease characterized by β-amyloid deposition in cerebral vessel walls, leading to hemorrhagic and ischemic injuries. The Boston criteria 2.0 guide CAA diagnosis based on clinical and neuroimaging findings. Although imaging-based phenotypes have been well-defined, data on CSF biomarkers remain limited. Integrating CSF and imaging markers may improve understanding of CAA disease patterns. This study evaluates associations between CSF and neuroimaging biomarkers in CAA.
Authors
- Massimo Filippi (ORCID: https://orcid.org/0000-0002-5485-0479)
- Mario Orrico
- Marco Bacigaluppi
- Beatrice Dell’Acqua
- Nicoletta Anzalone (ORCID: https://orcid.org/0000-0002-4249-2723)
- Giacomo Giacalone (ORCID: https://orcid.org/0000-0002-8834-4267)
- Marco Vabanesi (ORCID: https://orcid.org/0000-0002-8283-7079)
- Raffaella Chieffo (ORCID: https://orcid.org/0000-0003-2288-1702)
- Andrea Falini (ORCID: https://orcid.org/0000-0002-1461-8755)
- Anna Del Poggio (ORCID: https://orcid.org/0000-0002-7649-3214)
- Luisa Roveri (ORCID: https://orcid.org/0000-0003-3114-4405)
- Miryam Cannizzaro (ORCID: https://orcid.org/0000-0003-1471-3549)
Institutions
- Vita-Salute San Raffaele University (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Publication Details
- Journal
- Neurology Open Access
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1212/wn9.0000000000000026
- Citations
- 1
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39