Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients
Reconstruction of genome-wide evolutionary histories and characterization of genomic heterogeneity in Chinese lung adenocarcinoma provides insight into cancer evolution, which may contribute to improved treatment and diagnostic strategies for lung cancer patients. This article is part of a special series: Driving Cancer Discoveries with Computational Research, Data Science, and Machine Learning/AI.
Authors
- Jun Xiang
- Hongbing Shen (ORCID: https://orcid.org/0000-0002-2581-5906)
- Hongxia Ma (ORCID: https://orcid.org/0000-0002-9821-6955)
- Zhoufeng Wang (ORCID: https://orcid.org/0000-0002-7881-1837)
- Zihuan Zhao (ORCID: https://orcid.org/0000-0003-1311-2215)
- Yingjia Chen
- Yuanlin He (ORCID: https://orcid.org/0000-0001-7019-6756)
- Linnan Gong
- Juncheng Dai (ORCID: https://orcid.org/0000-0002-3909-5671)
- Cheng Wang (ORCID: https://orcid.org/0000-0002-8193-9276)
- Na Qin (ORCID: https://orcid.org/0000-0001-6878-9464)
- Congcong Chen (ORCID: https://orcid.org/0009-0008-0557-865X)
- Zhibin Hu (ORCID: https://orcid.org/0000-0002-8277-5234)
- Kai Wang (ORCID: https://orcid.org/0000-0003-3375-6552)
- Weimin Li (ORCID: https://orcid.org/0000-0003-0985-0311)
- Xianfeng Xu
- Meng Zhu (ORCID: https://orcid.org/0000-0001-5122-1733)
- Rong Yin (ORCID: https://orcid.org/0000-0002-9744-4251)
- Yue Jiang (ORCID: https://orcid.org/0000-0002-7725-272X)
- Yuan Xie
- Zhe Li
- Pan Tang
- Xin Wang
- Wenxin Luo (ORCID: https://orcid.org/0000-0003-2279-131X)
- Songwei Guo
- Lingfeng Bi (ORCID: https://orcid.org/0009-0001-8864-4737)
Institutions
- Harbin Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Suzhou Municipal Hospital (CN)
- Jiangsu Cancer Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Cancer Research
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1158/0008-5472.can-24-1799
- Citations
- 1
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- Chinese Academy of Medical Sciences
- Outstanding Youth Foundation of Jiangsu Province of China