Efficacy and Safety of Nintedanib in Japanese Patients With Early-Stage Idiopathic Pulmonary Fibrosis: A One-Year Interim Analysis from a Multicenter Observational Study in Kyushu and Okinawa, Japan
The findings of this interim analysis indicate that nintedanib has good efficacy, safety, and tolerability for early-stage IPF in real-world settings, outside randomized control trials.
Authors
- Kazuya Ichikado (ORCID: https://orcid.org/0000-0002-4840-2450)
- Hidenori Ichiyasu (ORCID: https://orcid.org/0000-0003-1773-8485)
- Noriho Sakamoto (ORCID: https://orcid.org/0000-0002-7577-476X)
- Hiroshi Ishimoto (ORCID: https://orcid.org/0000-0002-4374-2894)
- Kazuhiro Yatera (ORCID: https://orcid.org/0000-0002-2955-4432)
- Taiga Miyazaki (ORCID: https://orcid.org/0000-0002-0962-5758)
- Hiroshi Ishii (ORCID: https://orcid.org/0000-0002-2143-5922)
- Shimpei Morimoto (ORCID: https://orcid.org/0000-0002-5340-6851)
- Hiroshi Mukae (ORCID: https://orcid.org/0000-0002-1429-5706)
- Kazunori Tobino (ORCID: https://orcid.org/0000-0002-3456-6833)
- Naoki Hosogaya (ORCID: https://orcid.org/0000-0002-3229-2277)
- Masaki Okamoto (ORCID: https://orcid.org/0000-0002-9298-3504)
- Naoki Hamada (ORCID: https://orcid.org/0000-0001-9769-7999)
- Takashi Kido (ORCID: https://orcid.org/0000-0001-8338-0608)
- Takuto Miyramura
Institutions
- University of Miyazaki (JP)
- University of Nagasaki (JP)
- University of Occupational and Environmental Health Japan (JP)
- National Kyushu Medical Center (JP)
- Fukuoka University (JP)
- Fukuoka University Hospital (JP)
- Sasebo City General Hospital (JP)
- Saiseikai Kumamoto Hospital (JP)
- Kumamoto University Hospital (JP)
- Aso Iizuka Hospital (JP)
- Nagasaki University Hospital (JP)
- Nagasaki University (JP)
Publication Details
- Journal
- Clinical Therapeutics
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1016/j.clinthera.2025.05.007
- Citations
- 3
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- Kagoshima University
- Boehringer Ingelheim Japan
- University of Miyazaki Hospital
- Fukuoka University
- University of Miyazaki