Conformational Plasticity in Amyloid Assemblies: A Paradigm Shift from Structural Rigidity to Functional Adaptability
The divergence of conformational ensembles of hIAPP in response to different types of mutations and PTMs has been decoded by leveraging the scanning tunneling microscopy-based probability interpretation technique.
Authors
- Xiaoguang Wang (ORCID: https://orcid.org/0000-0002-4079-9596)
- Alan H. Weible
Institutions
- Sustainability Institute (ZA)
- The Ohio State University (US)
Publication Details
- Journal
- ACS Central Science
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1021/acscentsci.5c00983
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00