Ashwagandha, Withania somnifera (L.) Dunal, for the prophylaxis against SARS-CoV-2 infection: A multicentric randomized hydroxychloroquine controlled clinical trial in Indian health care workers
WS was found equivalent to HCQ as a prophylactic against SARS-CoV-2 infection with no safety concern. WS is thus inferred to be an effective and safe Ayurvedic intervention for prophylaxis against SARS-CoV-2 infection, and also as an immunobooster.
Authors
- Rahul Darnule (ORCID: https://orcid.org/0000-0002-2147-7073)
- Jaya Chakravarty (ORCID: https://orcid.org/0000-0001-9834-8053)
- Sangeeta Kansal (ORCID: https://orcid.org/0000-0001-5866-5724)
- Saurabh Pandey (ORCID: https://orcid.org/0000-0002-5339-095X)
- Rita Singh (ORCID: https://orcid.org/0000-0002-1223-2488)
- Akash Khobragade
- Jui Shah
- Dipti Kumbhar
- Dhaiwat Shukla
- Anil Avhad (ORCID: https://orcid.org/0000-0002-6807-2831)
- Anand More
- Anshul Srivastava (ORCID: https://orcid.org/0000-0002-7392-287X)
- Meena Yadav (ORCID: https://orcid.org/0000-0002-1966-2886)
- Arvind Chopra (ORCID: https://orcid.org/0000-0002-4347-9651)
- Nilima Kshirsagar (ORCID: https://orcid.org/0000-0002-9195-3143)
- Dilip M. Mondhe
- Ashish Amarsheda
- Sarita Kumari (ORCID: https://orcid.org/0000-0002-3836-3734)
- Divya Kajaria
- Manish Patel (ORCID: https://orcid.org/0000-0002-9407-8647)
- Paresh Panchal
- Priyanka Mishra
- Sonali Munot
- Snehalata Gajbhiye
- D. Himanshu Reddy
- Shobha Bhat
- Padmaja A Marathe
- Sandhya Kamat
- Raakhi Tripathi
- Vasuda Bhagat
- Renuka Kulkarni-Munshi
- Deepti Talmohite
- Jaee Parvatkar
- Jayashree Bhale
- Viswajanani Sattigeri
Institutions
- Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals (IN)
- King Edward Memorial Hospital and Seth G.S. Medical College (IN)
- King George's Medical University (IN)
- Topiwala National Medical College & BYL Nair Charitable Hospital (IN)
- National Institute of Ayurveda (IN)
- Employees State Insurance Post Graduate Institute of Medical Sciences and Research (IN)
- Sardar Vallabhbhai Patel University of Agriculture & Technology (IN)
- Cadila Pharmaceuticals (India) (IN)
- Indian Institute of Integrative Medicine (IN)
- Institute for Rheumatic Diseases (Japan) (JP)
- Employees' State Insurance Model Hospital (IN)
- Ministry of AYUSH (IN)
- Institute of Medical Sciences (IN)
- National Institute of Nutrition (IN)
- Sardar Patel University (IN)
Publication Details
- Journal
- Journal of Ayurveda and Integrative Medicine
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.jaim.2025.101135
- Citations
- 1
- Primary Topic
- Phytochemicals and Medicinal Plants
- Type
- article
- Field-Weighted Citation Impact
- 2.38
Funders
- Ministry of AYUSH, Government of India
- Department of Scientific and Industrial Research, Ministry of Science and Technology, India
- Indian Council of Medical Research
- Council of Scientific and Industrial Research, India
- Ministry of Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homoeopathy
- Savitribai Phule Pune University