Serotype distribution, virulence factors, and antimicrobial resistance profiles of Streptococcus agalactiae (Group B Streptococcus) isolated from pregnant women in the Brazilian Amazon
This is the first characterization of GBS in this region, revealing notable virulence and high susceptibility to first-line antibiotics. Six serotypes were identified, including Brazil's second report of serotype VI, emphasizing the genetic and epidemiological diversity of the Amazonian region. Moreover, given that the serotype distribution in this population corresponds to the most prevalent types worldwide, the hexavalent GBS conjugate vaccine could represent a promising strategy for this population, as it would theoretically cover 91.8% of the analyzed strains, if proven effective and made available in Brazil.
Authors
- Najla Benevides Matos (ORCID: https://orcid.org/0000-0002-7271-5764)
- Renata Santos Rodrigues (ORCID: https://orcid.org/0000-0001-7954-864X)
- Núcia Cristiane da Silva Lima (ORCID: https://orcid.org/0000-0001-8588-3188)
- Roger Lafontaine Mesquita Taborda (ORCID: https://orcid.org/0000-0002-1927-3055)
- Marcos Eduardo Passos da Silva (ORCID: https://orcid.org/0000-0002-4973-0181)
- Mariana Delfino Rodrigues (ORCID: https://orcid.org/0000-0003-0417-2910)
- Anjo Gabriel Carvalho (ORCID: https://orcid.org/0000-0002-1870-0465)
- Tatiana Castro Abreu Pinto (ORCID: https://orcid.org/0000-0002-7878-9377)
- Mayra Gyovana Leite Belém
- Nagilla Wynne dos Santos Dorneles (ORCID: https://orcid.org/0000-0001-5899-7905)
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Universidade Federal de Rondônia (BR)
- Faculdades Integradas Aparício Carvalho (BR)
- Fundação Oswaldo Cruz (BR)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-06-07
- DOI
- https://doi.org/10.1186/s12866-025-04077-2
- Citations
- 2
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação Oswaldo Cruz