Acetaldehyde exposure alters fibrin polymerization, fibrinolysis, and fibrin network structure in vitro
These results indicate that acetaldehyde exposure drives the formation of prothrombotic fibrin clots that are resistant to lysis, suggesting that endogenous or exogenous acetaldehyde exposure may influence thrombosis risk.
Authors
- Lauren G. Poole (ORCID: https://orcid.org/0000-0002-5405-5774)
- Waris Khan (ORCID: https://orcid.org/0000-0002-4286-5403)
- Rebecca A Risman (ORCID: https://orcid.org/0009-0009-4915-9139)
- Valerie J. Tutwiler (ORCID: https://orcid.org/0000-0003-1213-4447)
- Dongyan Hu (ORCID: https://orcid.org/0000-0002-2317-9918)
- S. de Rave
Institutions
- Rutgers, The State University of New Jersey (US)
- Johnson University (US)
- Environmental and Occupational Health Sciences Institute (US)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102921
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of Environmental Health Sciences