Development of high-content screening assay for gene silencing in adult sensory neurons
This platform enables rapid, cost-effective evaluation of hundreds to thousands of candidate genes in adult sensory neurons, facilitating identification of neurite growth regulators.
Authors
- Gunnar Poplawski (ORCID: https://orcid.org/0000-0002-1917-3441)
- David Do (ORCID: https://orcid.org/0000-0003-3604-5609)
- Richard Lie (ORCID: https://orcid.org/0000-0003-4389-7383)
- Rodrigo Lopez Gonzalez
- Grace Woodruff (ORCID: https://orcid.org/0000-0002-7052-1050)
- Phillip Canete
Institutions
- La Jolla Institute for Immunology (US)
- University of California San Diego (US)
- Cleveland Clinic Lerner College of Medicine (US)
Publication Details
- Journal
- Journal of Neuroscience Methods
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1016/j.jneumeth.2025.110500
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Veterans Affairs
- Dr. Miriam and Sheldon G. Adelson Medical Research Foundation
- Cleveland Clinic
- Cleveland Clinic Foundation
- National Institutes of Health