Intraoperative oxygen concentration and postoperative delirium in elderly patients undergoing major abdominal surgery: a prospective randomized controlled clinical trial
While 100% FiO₂ enhances cerebral oxygenation, it does not reduce POD incidence or neuroinflammatory markers compared to 40% FiO₂. High-concentration oxygen did not increase pulmonary complications but offered no clinical benefits in this cohort. Intraoperative FiO₂ should be titrated based on individualized patient needs.
Authors
- Tianzhu Tao (ORCID: https://orcid.org/0000-0001-6853-1324)
- Yue Shi (ORCID: https://orcid.org/0000-0002-0179-3853)
- Bo Ye (ORCID: https://orcid.org/0000-0001-5704-0327)
- Xiaojing Fan (ORCID: https://orcid.org/0000-0001-8686-8254)
- Shunpan Ji
Institutions
- Air Force General Hospital PLA (CN)
- China Medical University (CN)
Publication Details
- Journal
- International Journal of Colorectal Disease
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1007/s00384-025-04929-3
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00