An Online Interactive Map of Human Metabolic Pathways and Associated Genetic Disorders as a Tool for the Biochemistry Classroom

In a typical undergraduate biochemistry course, two main educational objectives include (1) understanding and applying how genetic mutations can influence protein structure and function, and (2) examining metabolic pathways of biomolecules to study cellular storage and fuel. Many times, these topics can seem disparate to students; therefore, we have developed a free, online resource that integrates known genetic mutations of enzymes important for human metabolism with a visualization of the associated metabolic pathways. The Metabolic Genetic Disorders Explorer can allow students to synthesize their knowledge of these concepts in a variety of ways.

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Publication Details

Journal
Journal of Chemical Education
Published
2025-06-06
DOI
https://doi.org/10.1021/acs.jchemed.4c01279
Primary Topic
Genetics, Bioinformatics, and Biomedical Research
Type
article
Field-Weighted Citation Impact
0.00

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article

An Online Interactive Map of Human Metabolic Pathways and Associated Genetic Disorders as a Tool for the Biochemistry Classroom

Hannah K. Parker, Julie A. Pollock, Beth Zizzamia
Journal of Chemical Education
Genetics, Bioinformatics, and Biomedical Research
article

An Online Interactive Map of Human Metabolic Pathways and Associated Genetic Disorders as a Tool for the Biochemistry Classroom

Hannah K. Parker, Julie A. Pollock, Beth Zizzamia
article en

Abstract

In a typical undergraduate biochemistry course, two main educational objectives include (1) understanding and applying how genetic mutations can influence protein structure and function, and (2) examining metabolic pathways of biomolecules to study cellular storage and fuel. Many times, these topics can seem disparate to students; therefore, we have developed a free, online resource that integrates known genetic mutations of enzymes important for human metabolism with a visualization of the associated metabolic pathways. The Metabolic Genetic Disorders Explorer can allow students to synthesize their knowledge of these concepts in a variety of ways.

Journal of Chemical Education
University of Richmond (US)
University of Richmond, School of Arts and Sciences, University of Richmond
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Openalex Percentile: Top 88%
Genetics, Bioinformatics, and Biomedical Research
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