Comprehensive analysis of m7G-related genes METTL1 and WDR4 for predicting prognosis and oncogenic functions in prostate cancer
Our study unveils the oncogenic roles of both METTL1 and WDR4 in prostate cancer development. Additionally, the prognostic model founded on METTL1 and WDR4 exhibits enhanced predictive precision for OS, thereby serving as a valuable clinical tool for prostate cancer.
Authors
- Cong Lai (ORCID: https://orcid.org/0000-0002-4729-104X)
- Jintao Hu (ORCID: https://orcid.org/0000-0003-3577-6944)
- Yelisudan Mulati (ORCID: https://orcid.org/0000-0001-6722-4867)
- Jiawen Luo (ORCID: https://orcid.org/0000-0002-2031-2912)
- Cheng Liu (ORCID: https://orcid.org/0000-0002-1185-1172)
- Junjie Wang (ORCID: https://orcid.org/0000-0002-5786-0146)
- Juanyi Shi
- Kewei Xu (ORCID: https://orcid.org/0000-0003-4649-4619)
- Degeng Kong
- Yunfei Xiao
Institutions
- Sun Yat-sen University (CN)
- Guangdong Province Stomatological Hospital (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Guangdong Provincial Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1007/s12672-025-02847-y
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China