Pulmonary hypertension induced right heart failure via upregulation of serum Dickkopf-1 expression
Elevated DKK1 levels are associated with worsening RV dysfunction in PH, suggesting a potential pathogenic role in PH-induced RHF. DKK1 may serve as a complementary biomarker and a potential therapeutic target in PH-related RHF.
Authors
- Hao Xu (ORCID: https://orcid.org/0000-0002-2424-9738)
- Junhua Ge (ORCID: https://orcid.org/0000-0002-3119-6478)
- Yimin Sun
- Haojie Zhang (ORCID: https://orcid.org/0009-0007-9455-5961)
- Ziqing Wang (ORCID: https://orcid.org/0009-0000-4702-4681)
- Jian Li (ORCID: https://orcid.org/0000-0003-2075-0119)
- Sarah Ren (ORCID: https://orcid.org/0009-0009-2899-7619)
- Qianqian Wang (ORCID: https://orcid.org/0009-0005-9308-0584)
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- International Journal of Cardiology
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1016/j.ijcard.2025.133481
- Citations
- 3
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- Natural Science Foundation of Shandong Province