[Clinical analysis of 72 children with Langerhans cell histiocytosis].
Skull is the most commonly affected site in pediatric LCH. The <i>BRAF-V600E</i> mutation is not related to clinical characteristics, efficacy, or prognosis. Elevated platelet count, risk organ involvement, and multisystem involvement are associated with poor prognosis, with risk organ involvement being an independent risk factor for 5-year EFS.
Authors
- Yu Yan (ORCID: https://orcid.org/0000-0001-5023-0654)
- Yixin Xiao (ORCID: https://orcid.org/0000-0002-8869-0397)
- Fanghua Ye (ORCID: https://orcid.org/0009-0003-7861-3894)
- Weixiong Jiang
- Wenjun Deng (ORCID: https://orcid.org/0009-0003-1735-9044)
- Liangchun Yang
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-05-15
- DOI
- https://doi.org/10.7499/j.issn.1008-8830.2412173
- Primary Topic
- Histiocytic Disorders and Treatments
- Type
- article