[Clinical correlation study between bone metabolism level and knee osteoarthritis pain].

Bone metabolism levels in the serum of patients with knee osteoarthritis are different from those of healthy people, and the difference between OC and t-PINP is the most obvious, and the concentration of t-PINP levels is positively correlated with pain symptoms in patients with KOA. However, the specific mechanism of correlation between the bone metabolism levels of patients with KOA and their pain symptoms needs to be further elucidated by basic experimental research as well as by enlarging the samples.

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Publication Details

Journal
PubMed
Published
2025-05-25
DOI
https://doi.org/10.12200/j.issn.1003-0034.20240038
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
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[Clinical correlation study between bone metabolism level and knee osteoarthritis pain].

Jun Duan, Yongqi Sun, Zezhong Liu, Xiaofeng Wang et al.
PubMed
Osteoarthritis Treatment and Mechanisms
article

[Clinical correlation study between bone metabolism level and knee osteoarthritis pain].

Jun Duan, Yongqi Sun, Zezhong Liu, Xiaofeng Wang, Guogang Luo, Bing Xu, Keqiang Guo, Xian-Liang Lai
article en

Abstract

Bone metabolism levels in the serum of patients with knee osteoarthritis are different from those of healthy people, and the difference between OC and t-PINP is the most obvious, and the concentration of t-PINP levels is positively correlated with pain symptoms in patients with KOA. However, the specific mechanism of correlation between the bone metabolism levels of patients with KOA and their pain symptoms needs to be further elucidated by basic experimental research as well as by enlarging the samples.

PubMedVol. 38(5)
Zhejiang Chinese Medical University (CN), Wenzhou Hospital of Traditional Chinese Medicine (CN), Xiangyang Hospital of Traditional Chinese Medicine (CN)
Osteoarthritis Treatment and Mechanisms
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