Outcome of intravesical doxorubicin installation in T1 non muscle invasive bladder cancer: experience from a tertiary hospital in Indonesia

In Indonesia, the proportion of non-muscle bladder cancer is low compared to other countries. Doxorubicin is currently one of options for adjuvant therapy for nonmuscle invasive bladder (NMIBC) that underwent transurethral resection of bladder tumor (TURBT). This study is aimed to evaluate the oncological outcome of doxorubicin intravesical. Eight consecutive T1 bladder patients who underwent TURBT with complete tumor resection, and received intravesical chemotherapy were enrolled in this study. All the clinical data were gathered retrospectively. One of eight patients did not respond to intravesical doxorubicin instillation. Patients were recorded with univocal, low grade and female patients. In conclusion, doxorubicin intravesical may be one of options. Despite a small number of samples were enrolled. This preliminary data showed promising results on intravesical doxorubicin instillation.

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Publication Details

Journal
Indonesian Journal of Biomedicine and Clinical Sciences
Published
2024-12-11
DOI
https://doi.org/10.22146/inajbcs.v56i4.18139
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
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article

Outcome of intravesical doxorubicin installation in T1 non muscle invasive bladder cancer: experience from a tertiary hospital in Indonesia

Andy Zulfiqqar, Adhika Restanto Purnomo
Indonesian Journal of Biomedicine and Clinical Sciences
Bladder and Urothelial Cancer Treatments
article

Outcome of intravesical doxorubicin installation in T1 non muscle invasive bladder cancer: experience from a tertiary hospital in Indonesia

Andy Zulfiqqar, Adhika Restanto Purnomo
article en

Abstract

In Indonesia, the proportion of non-muscle bladder cancer is low compared to other countries. Doxorubicin is currently one of options for adjuvant therapy for nonmuscle invasive bladder (NMIBC) that underwent transurethral resection of bladder tumor (TURBT). This study is aimed to evaluate the oncological outcome of doxorubicin intravesical. Eight consecutive T1 bladder patients who underwent TURBT with complete tumor resection, and received intravesical chemotherapy were enrolled in this study. All the clinical data were gathered retrospectively. One of eight patients did not respond to intravesical doxorubicin instillation. Patients were recorded with univocal, low grade and female patients. In conclusion, doxorubicin intravesical may be one of options. Despite a small number of samples were enrolled. This preliminary data showed promising results on intravesical doxorubicin instillation.

Indonesian Journal of Biomedicine and Clinical SciencesVol. 56(4)
Universitas Gadjah Mada (ID), Universitas Gunung Kidul (ID)
Openalex Percentile: Top 52%
Bladder and Urothelial Cancer Treatments
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