Long-term clinical outcomes of oral anticoagulation in the older patients with atrial fibrillation aged ≥80 years: a report from the GLORIA-AF registry phase III
Older age was independently associated with higher risk of death, major bleeding, TE and MACE. Compared with VKA, NOACs show improved effectiveness and safety in the older and patients with frailty, with similar efficacy across regions and ethnic groups.
Authors
- Tze-Fan Chao
- Menno V. Huisman (ORCID: https://orcid.org/0000-0003-1423-5348)
- Brian Olshansky (ORCID: https://orcid.org/0000-0002-6044-045X)
- Gregory Y.H. Lip (ORCID: https://orcid.org/0000-0002-7566-1626)
- Kui Hong
- Steven Ho Man Lam (ORCID: https://orcid.org/0000-0003-2147-0995)
- Giulio Francesco Romiti (ORCID: https://orcid.org/0000-0002-3788-8942)
- Yang Chen (ORCID: https://orcid.org/0000-0002-2808-6286)
- Bi Huang
- Yang Liu (ORCID: https://orcid.org/0000-0003-1381-9624)
- Hongyu Liu (ORCID: https://orcid.org/0000-0003-0383-8725)
Institutions
- University of Iowa (US)
- Nanchang University (CN)
- Medical University of Białystok (PL)
- University of Liverpool (GB)
- National Yang Ming Chiao Tung University (TW)
- Leiden University Medical Center (NL)
- Taipei Veterans General Hospital (TW)
- Liverpool Heart and Chest Hospital (GB)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Liverpool John Moores University (GB)
- Sapienza University of Rome (IT)
- Chongqing Medical University (CN)
- Aalborg University (DK)
Publication Details
- Journal
- Age and Ageing
- Published
- 2025-05-31
- DOI
- https://doi.org/10.1093/ageing/afaf139
- Citations
- 4
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 5.55