Spinal Metastasis of Glioblastoma: A Case Report

Spinal metastases originating from glioblastoma (GBM) are exceedingly rare and present significant clinical challenges. The physiopathology behind this phenomenon involves tumor spread via cerebrospinal fluid pathways, particularly in cases where the primary brain tumor is located near the ventricular or subarachnoid spaces. Diagnosing spinal metastases from GBM requires multimodal imaging, which is essential for both confirming the diagnosis and guiding treatment. Treatment options remain limited, with a focus on palliative care, as survival rates for patients with spinal involvement are poor. This case report discusses a 61-year-old woman with a history of glioblastoma who developed secondary spinal metastases, outlining the clinical presentation, diagnostic workup, and management challenges associated with these rare and aggressive metastases.