Coordination of SLC39A1 and DRP1 facilitates HCC recurrence by impairing mitochondrial quality control
SLC39A1 correlates with HCC recurrence and HCC mortality. Interaction of SLC39A1 and DRP1 facilitates HCC by regulating mitochondrial quality control. Specific peptide targeting SLC39A1 efficiently prevents HCC progression.
Authors
- Qiong Wu (ORCID: https://orcid.org/0000-0002-1572-1121)
- Lixin Cheng (ORCID: https://orcid.org/0000-0002-9427-383X)
- Dong Ji (ORCID: https://orcid.org/0000-0001-8214-462X)
- Rui Li (ORCID: https://orcid.org/0000-0001-5343-3027)
- Zhe Wang (ORCID: https://orcid.org/0000-0002-4950-9954)
- Yijin Wang (ORCID: https://orcid.org/0000-0002-3700-1766)
- Zhiqiang Cheng (ORCID: https://orcid.org/0000-0002-6916-747X)
- Fengjuan Chen (ORCID: https://orcid.org/0000-0002-1663-4812)
- Qingxian Cai
Institutions
- North Sichuan Medical University (CN)
- Jinan University (CN)
- Chinese PLA General Hospital (CN)
- Southern University of Science and Technology (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Clinical and Translational Medicine
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1002/ctm2.70362
- Citations
- 3
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 3.45
Funders
- National Natural Science Foundation of China