Pharmaceutical Formulation and in Vitro Evaluation of Herbal Anti – Fungal Cream

Abstract: The rising incidence of fungal infections has highlighted the urgent need for treatments that are both effective and safe. Herbal antifungal creams have gained attention as a viable alternative to synthetic products due to their natural composition, reduced side effects, and eco-friendly nature. This research is cantered on the formulation and evaluation of a topical herbal antifungal cream that utilizes plant-derived active ingredients known for their antifungal efficacy. Specifically, neem, aloe vera, and clove oil were chosen for their well-documented activity against fungal pathogens. The cream was developed using a stable emulsion base to ensure smooth texture and ease of application. A series of evaluations—including pH stability, spread ability, and antifungal effectiveness—were carried out to assess the product's overall quality and therapeutic potential. The findings revealed notable antifungal activity, along with desirable physical and chemical characteristics, suggesting that the cream is a promising solution for managing fungal skin infections. This study reinforces the value of herbal-based formulations in dermatological care, while also supporting environmentally sustainable healthcare alternatives.