Executive Dysfunction and Prefrontal Cortex Dysregulation in Early-Onset Parkinson’s Disease: An fNIRS Study
This study underscores the central role of PFC dysfunction in EOPD-related EF impairment, identifying abnormalities in the DLPFC, mPFC, and VLPFC as key contributors to cognitive decline. These results lay the groundwork for early detection of EF deficits and inform targeted interventions to mitigate cognitive decline in EOPD.
Authors
- Zhongrui Yan (ORCID: https://orcid.org/0000-0003-3447-3300)
- Haiyang Wang (ORCID: https://orcid.org/0000-0001-6148-4924)
- Zhanhua Liang (ORCID: https://orcid.org/0000-0001-6483-4758)
- Yiming Liu (ORCID: https://orcid.org/0009-0001-5272-6132)
Institutions
- Shandong University (CN)
- Dalian Medical University (CN)
- Jining First People's Hospital (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Qilu Hospital of Shandong University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Integrative Neuroscience
- Published
- 2025-05-22
- DOI
- https://doi.org/10.31083/jin36989
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39