Obesity-Derived Biomolecules Promote the Differentiation of THP1 Monocytes to Macrophages In Vitro
The results of this study add evidence to the role of obesity-derived biomolecules as non-canonical differentiation stimuli in macrophages, which could be relevant in contexts where these biomolecules are chronically overproduced, such as obesity, low-grade inflammation, type 2 diabetes, and cancer.
Authors
- Jonadab E. Olguín (ORCID: https://orcid.org/0000-0002-7255-1667)
- Nohemí Salinas-Jazmín (ORCID: https://orcid.org/0000-0002-9870-8650)
- Mónica Mendoza-Rodríguez (ORCID: https://orcid.org/0000-0003-3056-9997)
- Victoria Hernández-Gómez
- Luis I. Terrazas (ORCID: https://orcid.org/0000-0003-4649-4117)
- Valeria Gutiérrez-Almaraz
- Valentina García-Garay
Institutions
- Universidad Autónoma de Tlaxcala (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-05-23
- DOI
- https://doi.org/10.31083/fbl36637
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00