Comparative Analysis of the Bioactivity and Anti-Inflammatory Effects Against Endotoxin in Mitochondria for Transplantation: Impact of Muscle Origin in Rats
RSM emerges as the optimal source for mitochondrial extraction, demonstrating superior respiratory activity and significant protective effects against LPS-induced cell death and mitochondrial dysfunction. These findings provide critical insights into optimizing MT outcomes through the strategic selection of mitochondrial sources.
Authors
- Pei-Wen Chen
- Chi-Chen Huang (ORCID: https://orcid.org/0000-0002-8729-6873)
- Jung‐Shun Lee (ORCID: https://orcid.org/0000-0003-4268-2161)
- Po‐Hsuan Lee (ORCID: https://orcid.org/0000-0003-4034-9234)
- Huifang Chen (ORCID: https://orcid.org/0000-0001-5507-4216)
- Chia‐En Wong (ORCID: https://orcid.org/0000-0003-2434-955X)
- Heng-Juei Hsu (ORCID: https://orcid.org/0000-0003-2858-1954)
- Da-Wei Huang
- Mei Wu
Institutions
- Chia-Yi Christian Hospital (TW)
- Tainan Municipal Hospital (TW)
- National Cheng Kung University Hospital (TW)
- National Cheng Kung University (TW)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-05-20
- DOI
- https://doi.org/10.31083/fbl37367
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Cheng Kung University
- Ditmanson Medical Foundation Chia-Yi Christian Hospital