Interferon-α2b Modulates AMPA and Kainate Receptors and Alters Cross Talk of AMPA and NMDA Receptors in the Frog Vestibular Epithelium
IFN-α2b stimulates AMPARs and kainate receptors (KARs) through various mechanisms but has no direct effect on NMDA receptors (NMDARs). Interferon-activated AMPARs can stimulate NMDARs activity, thereby altering synaptic plasticity of the glutamatergic afferent synapse in vestibular epithelium.
Authors
- I. V. Ryzhova (ORCID: https://orcid.org/0000-0001-6243-9420)
- Т. В. Тобиас (ORCID: https://orcid.org/0000-0001-6034-8728)
- Alexander G. Markov (ORCID: https://orcid.org/0000-0002-2867-044X)
- Е. А. Вершинина (ORCID: https://orcid.org/0000-0002-8873-4409)
Institutions
- Pavlov Institute of Physiology of the Russian Academy of Sciences (RU)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-05-23
- DOI
- https://doi.org/10.31083/fbl38852
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00