Neuroprotective Effect of PBCA Nanoparticles Delivering pEGFP-BDNF in a Mouse Model of Intracerebral Hemorrhage
PBCA-pEGFP-BDNF NPs improves neurological function in experimental ICH mice at least in part related to increased BDNF expression and decreased p65 NF-κB signaling axis activation, suggesting that PBCA NPs might be a suitable pEGFP-BDNF-carrying delivery system for ICH treatment.
Authors
- Chunbo Chen (ORCID: https://orcid.org/0000-0001-5662-497X)
- Xing Guo (ORCID: https://orcid.org/0000-0002-4682-3083)
- Yu Xiong (ORCID: https://orcid.org/0000-0002-3491-6389)
- Xue Lai
Institutions
- Jinan University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- Journal of Integrative Neuroscience
- Published
- 2025-05-26
- DOI
- https://doi.org/10.31083/jin26971
- Citations
- 4
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 5.56