Mechanism of SLC1A5 Regulation of Glutamine Metabolism to Promote Ferroptosis Sensitivity in Endometriosis
This study confirmed the involvement of the ROS/<i>c-Myc</i>/<i>SLC1A5</i> pathway in regulating EMs sensitivity to ferroptosis and demonstrated the potential of Erastin as a therapeutic agent. Targeting this pathway offers a promising approach for the treatment of EMs.
Authors
- Mingxiu Wu
- Yuting Xiang (ORCID: https://orcid.org/0000-0003-2371-4973)
- Pengyu Cai
- Yu-Hang Zhang (ORCID: https://orcid.org/0009-0004-7119-1630)
- Jin Xie
- Yuyin Liu
- Bin Zhang
- Huai-Lung Ma
- H. Wu
Institutions
- Dongguan People’s Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-05-21
- DOI
- https://doi.org/10.31083/fbl36781
- Citations
- 1
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- Southern Medical University