163 Aspirin Utilization in Patients with Nonvalvular Atrial Fibrillation on Oral Anticoagulants in a Large Academic Medical Center
minor, 1 major), while 4 patients had 25 procedures post-2019, 16 on emicizumab (9 urgent, 22 minor, 3 major).Pre-2019 regimens included recombinant activated factor VII (rFVIIa) 90 mcg/kg every 2 hours (n=1), activated prothrombin complex concentrate 50 units/kg every 12 hours (n=1), or both (n=1), with no bleeds.Post-2019 regimens included rFVIIa 90 mcg/kg every 2 hours (n=5), 75 mcg/kg every 4 hours (n=3), and rFVIII 50 units/kg every 12 hours (n=4).Bleeding-related dose escalation occurred following 1 procedure pre-2019 and 5 post-2019.Conclusion:
Authors
- Jennifer Mazur
- Aulbrey Drisaldi (ORCID: https://orcid.org/0000-0002-4971-7358)
- Joli D. Fermo
- Emily Ware (ORCID: https://orcid.org/0000-0002-1849-7401)
- Morgan Quinn
- Stephen D. Miller (ORCID: https://orcid.org/0000-0002-9556-0718)
- Dana Cruse
- Andrew Galascio
Institutions
- Medical University of South Carolina (US)
- Pfizer (United States) (US)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102768
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00