155 Evaluating the Clinical Utility and Appropriateness of Four-Factor Prothrombin Complex Concentrates for Anticoagulation Reversal at an Urban, Community Academic Hospital
Background: Four factor-prothrombin complex concentrate (4F-PCC) is approved for the urgent reversal of vitamin K antagonists in patients with major bleeding or the need for an urgent procedure. Off-label uses including the reversal of DOACs and as factor replacement intraoperatively are not without risk and cost, and appropriate utility should be protocolized.
Authors
- Youssef Bessada (ORCID: https://orcid.org/0000-0001-5999-9099)
- Nicole Thurnherr
Institutions
- University of Connecticut (US)
- Saint Francis University (US)
- Saint Francis Hospital & Medical Center (US)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102809
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00