98 Derivation and Validation of a Pharmacogenetic-guided Warfarin Dosing Algorithm in an Arab Population Residing in Qatar
Introduction: A number of studies have demonstrated the superiority of genotype guided warfarin dosing when compared to other methods. Internationally validated algorithms are also available and although studied in diverse populations they were not validated in the Arab population. This research aims to derive and validate a genotype-guided warfarin dosing algorithm in an Arab population and compare its results to an internationally validated genotype-guided warfarin dosing algorithm (Gage et al.
Authors
- Amr Mohamed Fahmi (ORCID: https://orcid.org/0000-0002-1502-6700)
- Hazem Elewa (ORCID: https://orcid.org/0000-0003-1594-1199)
- Mohamed Saad (ORCID: https://orcid.org/0000-0002-2221-4216)
- Loulia Bader (ORCID: https://orcid.org/0000-0001-9276-6959)
- Abdel-Naser Y Elzouki (ORCID: https://orcid.org/0000-0002-9132-1752)
- Osama Abdelsamad (ORCID: https://orcid.org/0000-0003-0262-2076)
- Ahmed Mahfouz (ORCID: https://orcid.org/0000-0002-6253-1670)
- Mohamed Nabil (ORCID: https://orcid.org/0000-0001-8509-0145)
- Mohamed Kassem (ORCID: https://orcid.org/0000-0003-1398-5905)
- Ahmed El Bardissy
Institutions
- Hamad Medical Corporation (QA)
- Qatar University (QA)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102778
- Primary Topic
- Pharmacogenetics and Drug Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00