61 Warfarin and GLP-1 Receptor Agonist Interaction Effects on Time in Therapeutic Range

Introduction: Warfarin is a commonly prescribed anticoagulant monitored using INR. Maximizing time in therapeutic range (TTR) is crucial for preventing stroke and major hemorrhage. GLP-1 receptor agonists manage diabetes and promote weight loss. While no known interactions exist between warfarin and GLP1-RA, secondary interactions due to gastrointestinal side effects cannot be ruled out. This study aimed to determine the impact of GLP-1 therapy initiation on INR control in patients receiving warfarin.