133 Argatroban Use in Therapeutic Plasma Exchange (TPE): A Case of Dynamic Anticoagulation Response

Background: Therapeutic Plasma Exchange (TPE) removes circulating autoantibodies, immune complexes, and other pathogenic substances. TPE also removes circulating coagulation factors including thrombin. Warfarin can be used during TPE, but the anticoagulant effect may be increased. There is little evidence surrounding other anticoagulants. This is the first documented case reviewing the impact of TPE on concomitant argatroban, a direct thrombin inhibitor.

Authors

Publication Details

Journal
Research and Practice in Thrombosis and Haemostasis
Published
2025-05-01
DOI
https://doi.org/10.1016/j.rpth.2025.102779
Citations
1
Primary Topic
Heparin-Induced Thrombocytopenia and Thrombosis
Type
article
Field-Weighted Citation Impact
2.01
Controls
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article

133 Argatroban Use in Therapeutic Plasma Exchange (TPE): A Case of Dynamic Anticoagulation Response

Jennifer E. Stanton, Alexander R. Nixon
1 citations
Research and Practice in Thrombosis and Haemostasis
Heparin-Induced Thrombocytopenia and Thrombosis
2.01
article

133 Argatroban Use in Therapeutic Plasma Exchange (TPE): A Case of Dynamic Anticoagulation Response

Jennifer E. Stanton, Alexander R. Nixon
article en
1 citations

Abstract

Background: Therapeutic Plasma Exchange (TPE) removes circulating autoantibodies, immune complexes, and other pathogenic substances. TPE also removes circulating coagulation factors including thrombin. Warfarin can be used during TPE, but the anticoagulant effect may be increased. There is little evidence surrounding other anticoagulants. This is the first documented case reviewing the impact of TPE on concomitant argatroban, a direct thrombin inhibitor.

Research and Practice in Thrombosis and HaemostasisVol. 9
Good health and well-being
Openalex Percentile: Top 15%
Heparin-Induced Thrombocytopenia and Thrombosis
2.01
DOIOpen Access PDFOpenAlex
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133 Argatroban Use in Therapeutic Plasma Exchange (TPE): A Case of Dynamic Anticoagulation Response — Jennifer E. Stanton, Alexander R. Nixon · Research and Practice in Thrombosis and Haemostasis (2025) | TGRS Research Map | TGRS